This simple yet flavorful chicken breast recipe is perfect for a quick weeknight dinner or a meal prep option. The combination of creamy mayonnaise or Greek yogurt, savory Parmesan cheese, and a blend of spices creates a rich and satisfying coating for the chicken breasts. Baked to perfection, this dish is both easy to make and delicious to enjoy. Whether you’re serving it alongside roasted vegetables, a salad, or mashed potatoes, this chicken breast recipe will become a go-to favorite in your meal rotation.
The beauty of this recipe is in its simplicity. With just a few basic ingredients and minimal prep, you can have a flavorful, tender chicken breast on the table in under an hour. The addition of Parmesan cheese and seasonings provides a rich, comforting flavor without the need for heavy sauces. Plus, using Greek yogurt as a substitute for mayonnaise makes it a healthier option while still delivering the creamy texture that makes this dish irresistible.
Why You’ll Love This Recipe
This chicken breast recipe is not only easy and quick to prepare, but it’s also versatile and packed with flavor. You’ll love the golden, crispy exterior and the tender, juicy inside of the chicken. The combination of garlic powder, onion powder, and paprika creates a perfectly balanced seasoning that enhances the chicken without overpowering it. This recipe is also adaptable to suit various dietary preferences, with the option to use Greek yogurt for a lighter, healthier alternative to mayonnaise. Plus, it’s a great option for meal prepping, as the chicken breasts can be stored and enjoyed throughout the week. Whether you’re cooking for one or feeding a family, this recipe will quickly become a staple in your kitchen.
Ingredients
- Boneless, skinless chicken breasts
- Mayonnaise (or Greek yogurt for a lighter option)
- Grated Parmesan cheese
- Garlic powder
- Onion powder
- Paprika
- Salt and pepper to taste
- Fresh parsley for garnish (optional)
Variations
- Lemon Herb Chicken: Add a tablespoon of fresh lemon juice and a teaspoon of dried oregano to the seasoning mix for a bright, herby flavor.
- Spicy Chicken: Incorporate a teaspoon of cayenne pepper or chili powder to give the chicken a little extra heat.
- Cheese Variations: Swap Parmesan cheese for other cheeses like cheddar or mozzarella for a different flavor profile.
- Low-Carb Option: For a keto-friendly alternative, use a low-carb mayonnaise and serve the chicken with a side of leafy greens or cauliflower mash.
How to Make the Recipe
Step 1: Preheat the Oven
Preheat your oven to 375°F (190°C) to ensure it’s hot enough to bake the chicken breasts evenly.
Step 2: Prepare the Chicken
Place the chicken breasts on a clean cutting board and season both sides with salt, pepper, garlic powder, onion powder, and paprika.
Step 3: Mix the Coating
In a small bowl, combine mayonnaise (or Greek yogurt) with grated Parmesan cheese. Stir until well combined.
Step 4: Coat the Chicken
Spread the mayonnaise mixture generously over the top of each chicken breast, covering them completely.
Step 5: Bake the Chicken
Place the coated chicken breasts on a baking sheet lined with parchment paper or aluminum foil. Bake in the preheated oven for 25-30 minutes or until the chicken reaches an internal temperature of 165°F (74°C) and the top is golden brown.
Step 6: Garnish and Serve
Once the chicken is cooked through, remove it from the oven and let it rest for a few minutes before serving. Garnish with fresh parsley, if desired, and serve immediately.

Tips for Making the Recipe
- Even Cooking: If the chicken breasts are very thick, consider slicing them horizontally to ensure even cooking and to reduce baking time.
- Make it Crispy: For a crispier top, you can broil the chicken for 2-3 minutes at the end of the baking process.
- Check Temperature: Always use a meat thermometer to check for doneness, ensuring the chicken reaches an internal temperature of 165°F (74°C).
- Marinate for Extra Flavor: For extra flavor, marinate the chicken in the seasoning mixture for 30 minutes to an hour before baking.
- Leftover Use: Leftover chicken works great in salads, wraps, or sandwiches.
How to Serve
This baked chicken breast pairs wonderfully with a variety of sides. Serve it alongside roasted vegetables, mashed potatoes, or a fresh garden salad. For a lighter option, serve it with steamed broccoli or a quinoa salad. If you’re looking for a more indulgent side, creamy mashed potatoes or garlic bread would complement the chicken perfectly.
Make Ahead and Storage
Storing Leftovers
Store leftover chicken breasts in an airtight container in the refrigerator for up to 3-4 days. The chicken will retain its flavor and moisture, making it a great option for meal prep.
Freezing
To freeze, place the cooked chicken breasts in a freezer-safe bag or container. They can be stored in the freezer for up to 3 months. When ready to eat, thaw overnight in the refrigerator and reheat in the oven at 350°F (175°C) until warmed through.
Reheating
To reheat, place the chicken breasts in a preheated oven at 350°F (175°C) for 10-15 minutes or until they are heated through. For a faster option, you can also reheat in the microwave for 1-2 minutes.

FAQs
1. Can I use skin-on chicken breasts?
Yes, you can use skin-on chicken breasts, but the cooking time may be slightly longer. Make sure the internal temperature reaches 165°F (74°C) to ensure it’s cooked through.
2. Can I substitute mayonnaise with sour cream?
Yes, sour cream can be used as a substitute for mayonnaise for a tangy flavor.
3. Is this recipe gluten-free?
Yes, this recipe is naturally gluten-free as long as the ingredients (such as the mayonnaise and Parmesan) are certified gluten-free.
4. Can I use frozen chicken breasts?
It’s best to thaw frozen chicken breasts before cooking to ensure even cooking. You can thaw them in the refrigerator overnight.
5. How can I make the chicken more flavorful?
Marinate the chicken in the seasoning mix for 30 minutes before baking to infuse it with more flavor.
6. Can I use a different cheese?
Yes, you can substitute Parmesan with other cheeses like cheddar or mozzarella, depending on your preference.
7. How long does this chicken stay good in the fridge?
The cooked chicken will stay fresh in the fridge for up to 3-4 days.
8. Can I make this recipe ahead of time?
You can prepare the chicken ahead of time and refrigerate it with the mayonnaise mixture. Then, bake it when you’re ready to serve.
9. Can I bake this recipe on a rack instead of a baking sheet?
Yes, using a baking rack will allow air to circulate around the chicken for even cooking and a crispier texture.
10. Can I use chicken thighs instead of breasts?
Yes, you can use chicken thighs. Just adjust the cooking time as thighs may take a bit longer to cook through.
Conclusion
This chicken breast recipe is an easy, versatile, and flavorful dish that’s perfect for any night of the week. With just a few ingredients and minimal prep, you can create a meal that’s both healthy and delicious. Whether you’re serving it with roasted vegetables or a light salad, this recipe will become a staple in your kitchen. The option to substitute ingredients for a lighter, healthier version or to customize the seasoning allows for endless variations, making it a recipe you’ll return to again and again.
Print
Chicken Breast Recipe
- Total Time: 35 minutes
- Yield: 4 servings 1x
Description
This chicken breast recipe is easy to make and packed with flavor. Tender chicken breasts are coated in a creamy mixture of mayonnaise and Parmesan cheese, then seasoned with garlic, onion powder, and paprika for a deliciously savory dish. It’s the perfect dinner for a busy weeknight!
Ingredients
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4 boneless, skinless chicken breasts
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½ cup mayonnaise (or Greek yogurt for a lighter option)
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½ cup grated Parmesan cheese
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1 tsp garlic powder
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1 tsp onion powder
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½ tsp paprika
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Salt and pepper to taste
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Fresh parsley for garnish (optional)
Instructions
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Preheat your oven to 375°F (190°C).
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In a medium bowl, mix together mayonnaise (or Greek yogurt), Parmesan cheese, garlic powder, onion powder, paprika, salt, and pepper until well combined.
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Place the chicken breasts on a baking sheet lined with parchment paper or lightly greased.
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Spread the creamy Parmesan mixture evenly over the chicken breasts, covering them completely.
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Bake in the preheated oven for 25–30 minutes, or until the chicken is cooked through and reaches an internal temperature of 165°F (74°C).
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Remove from the oven and let the chicken rest for 5 minutes.
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Garnish with fresh parsley (optional) and serve hot.
Notes
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For a lighter version, substitute mayonnaise with Greek yogurt.
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You can also add other spices like Italian seasoning or lemon zest for additional flavor.
- Ensure the chicken breasts are of equal thickness for even cooking. If they’re uneven, consider gently pounding them for a consistent texture.
- Prep Time: 10 minutes
- Cook Time: 25 minutes
- Category: Main Dish
- Method: Baking
- Cuisine: American