If you’re craving something creamy, bold, and comforting without all the cleanup, this One Pot Cajun Chicken Alfredo is your new weeknight go-to. Loaded with flavor, this dish blends tender, bite-sized chicken breast pieces with a perfectly spiced Cajun seasoning and a velvety Alfredo-style sauce. With everything cooked in just one pan—including the pasta—it’s a hassle-free meal that’s as convenient as it is delicious.

The magic of this recipe lies in its simplicity. No need for separate pots or draining pasta; everything cooks together, soaking up all those savory Cajun and garlicky flavors. The fettuccine becomes tender right in the sauce, which is made from a combination of chicken broth, half and half, and freshly grated parmesan for that irresistible creamy finish. The result? A comforting, restaurant-quality pasta dish that comes together with minimal effort.

Whether you’re feeding a hungry family, impressing guests, or meal-prepping for the week, this dish delivers flavor and comfort in every bite. It’s rich without being heavy, spicy without being overwhelming, and satisfying without a sink full of dishes. If you love creamy pasta dishes with a little Southern kick, this One Pot Cajun Chicken Alfredo is guaranteed to make its way into your regular dinner rotation.

Why You’ll Love This Recipe

One-pot convenience: Fewer dishes and easier cleanup.
Bold Cajun flavor: A delicious mix of spice and creaminess.
Family-friendly: Mild enough for kids but flavorful enough for adults.
Quick and easy: Ready in about 30 minutes from start to finish.
Comfort food classic: Creamy pasta, tender chicken, and parmesan—what’s not to love?

Ingredients

Boneless skinless chicken breast
Olive oil
Cajun seasoning
Minced garlic
Chicken broth
Half and half
Salt
Ground black pepper
Garlic powder
Fettuccine pasta
Grated parmesan cheese

Variations

Make it spicier: Add cayenne pepper or extra Cajun seasoning for more heat.
Use different pasta: Penne, linguine, or spaghetti work well too.
Add vegetables: Bell peppers, spinach, or mushrooms make great additions.
Swap the protein: Use shrimp, sausage, or even tofu for a different twist.
Make it lighter: Use milk instead of half and half and reduce the cheese slightly.

How to Make the Recipe

Step 1

Heat olive oil in a large skillet or Dutch oven over medium heat. Add the bite-sized chicken breast pieces.

Step 2

Sprinkle the chicken with Cajun seasoning and sauté until browned on all sides and cooked through.

Step 3

Add minced garlic and sauté for another 30 seconds until fragrant.

Step 4

Pour in the chicken broth and half and half. Stir in salt, black pepper, and garlic powder.

Step 5

Add the uncooked fettuccine pasta, making sure it is submerged in the liquid as much as possible.

Step 6

Bring to a gentle simmer. Cover and cook for about 12–15 minutes, stirring occasionally, until the pasta is tender and the sauce has thickened.

Step 7

Remove from heat and stir in grated parmesan cheese until melted and fully combined.

Step 8

Let sit for a few minutes to thicken further before serving.

Tips for Making the Recipe

Stir the pasta frequently while cooking to prevent it from sticking together.
Slice the chicken evenly so it cooks uniformly and quickly.
Use freshly grated parmesan for the best flavor and texture.
Adjust Cajun seasoning to taste depending on spice preference.
Don’t overcook the pasta—check it a minute or two before the suggested time.

How to Serve

Serve hot with a sprinkle of extra parmesan and chopped parsley.
Pair with garlic bread or a crisp green salad for a complete meal.
Add a squeeze of lemon juice for a fresh, zesty finish.
Serve alongside roasted vegetables or steamed broccoli for added nutrition.
Garnish with red pepper flakes if you like extra spice.

Make Ahead and Storage

Storing Leftovers

Cool completely and store in an airtight container in the refrigerator for up to 3 days.

Freezing

Freeze in portioned containers for up to 2 months. Be aware that the sauce may slightly separate when reheated.

Reheating

Reheat on the stove over low heat, adding a splash of milk or broth to bring back creaminess. Microwave in short intervals, stirring in between.

FAQs

1. Can I use pre-cooked chicken for this recipe?

Yes, just add it after the broth and cream are simmering, and reduce the initial cook time.

2. Is Cajun seasoning very spicy?

It depends on the brand, but most are moderately spicy. Adjust to your preference.

3. Can I substitute the half and half?

Yes, use heavy cream for a richer dish or whole milk for a lighter version.

4. What if I don’t have fettuccine?

Any pasta that holds sauce well—like penne or linguine—will work.

5. Can I double this recipe?

Yes, just use a larger pot and stir frequently to ensure even cooking.

6. How do I prevent the pasta from sticking?

Stir regularly during cooking and ensure there’s enough liquid covering the pasta.

7. Can I add cheese other than parmesan?

Yes, shredded mozzarella or a blend of Italian cheeses works well.

8. Is this dish gluten-free?

Not unless you use gluten-free pasta and verify the Cajun seasoning is gluten-free.

9. Can I make this vegetarian?

Yes, omit the chicken and use a plant-based protein or vegetables instead.

10. What sides go best with Cajun Chicken Alfredo?

Garlic bread, Caesar salad, or roasted veggies are all great complements.

Conclusion

One Pot Cajun Chicken Alfredo is the perfect fusion of bold flavors, creamy pasta, and no-fuss cooking. Whether you’re feeding a family or meal prepping for the week, this satisfying dish offers a spicy, savory punch in every bite—all while saving you time in the kitchen. With endless customization options and simple ingredients, it’s a reliable, crowd-pleasing dinner that never disappoints.